Lunenfeld-Tanenbaum Research Institute

Prosserman Centre for Population Health Research

     Selected Publications (2017 -- )

  1. Sarma S, Hodzic-Santor B, Raissi A, Colacci M, Verma AA, Razak F, Højbjerg Lassen MC, Fralick M. Association of sodium glucose co-transporter-2 inhibitors with risk of diabetic ketoacidosis among hospitalized patients: A multicentre cohort study. J Diabetes Complications. 2024 Sep;38(9):108827. doi: 10.1016/j.jdiacomp.2024.108827. Epub 2024 Jul 29. PMID: 39096768.

  2. Lassen MCH, Colacci M, Pareek M, Lee SG, Gislason G, Fralick M, Biering-Sørensen T. Association Between SGLT2 Inhibitor Use and Change in Hemoglobin Among Adults with Diabetes: A Nationwide Cohort Study. J Gen Intern Med. 2024 Aug;39(10):1945-1947. doi: 10.1007/s11606-024-08640-x. Epub 2024 Apr 9. PMID: 38594550

  3. E Garg, P Arguello-Pascualli, O Vishnyakova, AR Halevy, S Yoo, JD Brooks, SB Bull, F Gagnon, CMT Greenwood, RJ Hung, JF Lawless, J Lerner-Ellis, JK Dennis, RJS Abraham, J-M Garant, B Thiruvahindrapuram, SJM Jones, HostSeq Implementation Committee, LJ Strug, AD Paterson, L Sun, LT Elliott. Canadian COVID-19 host genetics cohort replicates known severity associations, PLoS Genetics, 20(3), 22 March 2024, e1011192. [full texts]

  4. Wainberg, M., Forde, N.J., Mansour, S. et al. Genetic architecture of the structural connectome. Nat Commun 15, 1962 (2024). [full texts]
  5. Maan, H., Zhang, L., Yu, C... Campbell K., Wang, B. Characterizing the impacts of dataset imbalance on single-cell data integration. Nat Biotechnol (2024). [full texts]  

  6. Fang, C., Selega, A. & Campbell, K.R. Beyond benchmarking and towards predictive models of dataset-specific single-cell RNA-seq pipeline performance. Genome Biol 25, 159 (2024). [full texts]  

  7. Warkentin MT, Al-Sawaihey H, Lam S, Liu G, Diergaarde B, Yuan JM, Wilson DO, Atkar-Khattra S, Grant B, Brhane Y, Khodayari-Moez E, Murison KR, Tammemagi MC, Campbell KR, Hung RJ. Radiomics analysis to predict pulmonary nodule malignancy using machine learning approaches. Thorax 2024.doi: 10.1136/thorax-2023-220226. PMID: 38195644
  8. Geuenich, M.J., Gong, Dw. & Campbell, K.R. The impacts of active and self-supervised learning on efficient annotation of single-cell expression data. Nat Commun 15, 1014 (2024). [full texts] 

  9. Finegold KE, Knight JA, Hung RJ, Ssewanyana D, Wong J, Bertoni, K, Adel Khani N, Watson H, Levitan, R, Jenkins J, Matthews, S, Wade, M.. Cognitive and Emotional Well-Being of Preschool Children Before and During the COVID-19 Pandemic. JAMA Netw Open. 2023;6(11):e2343814. [full texts]

  10. Khodayari Moez E, Warkentin MT, Brhane Y, Lam S, Field JK, Liu G, Zulueta JJ, Valencia K, Mesa-Guzman M, Nialet AP, Atkar-Khattra S, Davies MPA, Grant B, Murison K, Montuenga LM, Amos CI, Robbins HA, Johansson M, Hung RJ. Circulating proteome for pulmonary nodule malignancy. J Natl Cancer Inst. 2023 Sep 7;115(9):1060-1070. [Full texts]
  11. Xu, J., Xu, W., Choi, J., Brhane, Y., Christiani, D. C., Kothari, J., McKay, J., Field, J. K., Davies, M. P. A., Liu, G., Amos, C. I., Hung, R. J., & Briollais, L. (2023). Large-scale whole exome sequencing studies identify two genes,CTSL and APOE, associated with lung cancer. PLoS genetics19(9), e1010902.[Full texts] 

  12. C XuSB Bull. Penalized maximum likelihood inference under the mixture cure model in sparse data, Statistics in Medicine, 2023 Jun 15;42(13):2134-2161. PMID: 36964996
  13. Cheng, S., McLaughlin, J. R., Brown, M. C., Al-Sawaihey, H., Rutka, J., Bouffet, E., Hawkins C, Cairney AE, Ranger A, Fleming AJ, Johnston D, Greenberg M, Malkin D, Hung, R. J. (2023). Maternal and childhood medical history and the risk of childhood brain tumours: a case–control study in Ontario, Canada. British Journal of Cancer, 1–7. [Full texts]

  14. Retnakaran R, Pu J, Emery A, Harris SB, Reichert SM, Gerstein HC, McInnis N, Kramer CK, Zinman B. Determinants of sustained stabilization of beta-cell function following short-term insulin therapy in type 2 diabetes. Nat Commun 2023; 14(1):4514.[Full texts]

  15. M Brossard, AD Paterson, O Espin-Garcia, RV Craiu, SB Bull. Characterization of direct and/or indirect genetic associations for multiple traits in longitudinal studies of disease progression,Genetics, 225(1), September 2023, iyad119. PMID: 37369448

  16. Warkentin, M. T., Tammemägi, M. C., Espin-Garcia, O., Budhathoki, S., Liu, G., & Hung, R. J. (2022). Lung Cancer Absolute Risk Models for Mortality in an Asian Population using the China Kadoorie Biobank. Journal of the National Cancer Institute114(12), 1665–1673. PMID: 36083018
  17. Selega, A., Campbell, K.R., (2022) Multi-objective Bayesian Optimization with Heuristic Objectives for Biomedical and Molecular Data Analysis Workflows. bioRxiv 2022.06.08.495370 [Full texts]

  18.  Retnakaran, R., Ye, C., Emery, A., Kramer, C. K., & Zinman, B. (2022). The metabolic effects of adding exenatide to basal insulin therapy when targeting remission in early type 2 diabetes in a randomized clinical trial. Nature Communications13(1), 6109. PMID: 36244997

  19. Goodwin, P.J, Chen b., Gelmon K. A., Whelan, T.J,. Ennis, M., Lemieux, J., Ligibel J.A., Hershman D.L., Mayer I.A., Hobday T.J., Bliss J.M., Rastogi P.,Rabaglio-Poretti M., Mukherjee S.D., Mackey J.R., Abramson V.G., Oja C., Wesolowski R., Thompson A.M., Rea, D.W., Stos P.M., Shepherd L.E., Stambolic V., Parulekar, W.R. (2022). Effect of metformin vs placebo on invasive disease-free survival in breast cancer: the MA.32 randomized clinical trial: the MA.32 randomized clinical trial. JAMA 327: 1963-1973. PMID: 35608580

  20. Lye, J. M., Knight, J. A., Arneja, J., Seeto, R. A., Wong, J., Adel Khani, N., Brooks, J. D., Levitan, R. D., Matthews, S. G., Lye, S. J., & Hung, R. J. (2022). Maternal acetaminophen use and cognitive development at 4 years: the Ontario Birth Study. Pediatric Research, 1–5. Advance online publication. PMID: 35794252

  21. Horwitz, J., Wen, S. W., Tan, H., Zhou, S., Ye, C., Shen, M., & Retnakaran, R. (2022). Analysis of Preconception Paternal Smoking and Neonatal Outcomes. JAMA Network Open5(1), e2144527. PMID: 35061043

  22. Cheng, S., McLaughlin, J. R., Brown, M. C., Al-Sawaihey, H., Rutka, J., Bouffet, E., Hawkins, C., Cairney, A. E., Ranger, A., Fleming, A. J., Johnston, D., Greenberg, M., Malkin, D., & Hung, R. J. (2022). Childhood head trauma and the risk of childhood brain tumours: A case-control study in Ontario, Canada. International Journal of Cancer150(5), 795–801. PMID: 34520575

  23. Zhang, C. X. W., Okeke, J. C., Levitan, R. D., Murphy, K. E., Foshay, K., Lye, S. J., Knight, J. A., & Matthews, S. G. (2022). Evaluating depression and anxiety throughout pregnancy and after birth: impact of the COVID-19 pandemic. American Journal of Obstetrics & Gynecology MFM4(3), 100605. PMID: 35257937

  24. Retnakaran, R., Ye, C., Hanley, A. J., Connelly, P. W., Sermer, M., Zinman, B., & Hamilton, J. K. (2022). Treating Gestational Diabetes Reduces Birth Weight but Does Not Affect Infant Adiposity Across the 1st Year of Life. Diabetes Care45(5), 1230–1238.  PMID: 35259243.

  25. Briollais, L., Rustand, D., Allard, C., Wu, Y., Xu, J., Rajan, S. G., Hivert, M. F., Doyon, M., Bouchard, L., McGowan, P. O., Matthews, S., & Lye, S. (2021). DNA methylation mediates the association between breastfeeding and early-life growth trajectories. Clinical Epigenetics13(1), 231. PMID: 34937578

  26. Geuenich, M. J., Hou, J., Lee, S., Ayub, S., Jackson, H. W., & Campbell, K. R. (2021). Automated assignment of cell identity from single-cell multiplexed imaging and proteomic data. Cell Systems12(12), 1173–1186.e5. PMID: 34536381.

  27. Brossard M., Paterson A.D. , Espin-Garcia, O., , Craiu R.V., Bull, S.B, . (2021) Characterization of direct and/or indirect genetic associations for multiple traits in longitudinal studies of disease progression. medRxiv 2021.05.10.21256880 [Full texts]

  28. Choi, Y. H., Terry, M. B., Daly, M. B., MacInnis, R. J., Hopper, J. L., Colonna, S., Buys, S. S., Andrulis, I. L., John, E. M., Kurian, A. W., & Briollais, L. (2021). Association of Risk-Reducing Salpingo-Oophorectomy With Breast Cancer Risk in Women With BRCA1 and BRCA2 Pathogenic Variants. JAMA Oncology7(4), 585–592. PMID: 33630024

  29. Hung, R. J., Warkentin, M. T., Brhane, Y., Chatterjee, N., Christiani, D. C., Landi, M. T., Caporaso, N. E., Liu, G., Johansson, M., Albanes, D., Marchand, L. L., Tardon, A., Rennert, G., Bojesen, S. E., Chen, C., Field, J. K., Kiemeney, L. A., Lazarus, P., Zienolddiny, S., Lam, S., … Amos, C. I. (2021). Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model. Cancer Research81(6), 1607–1615 1.  PMID: 33472890.

  30. Choi, Y. H., Terry, M. B., & Briollais, L. (2021). Bilateral Salpingo-Oophorectomy to Reduce Breast Cancer Risk in Women With Germline BRCA1 or BRCA2 Pathogenic Variants-Caution Needed-Reply. JAMA Oncology7(9), 1402. PMID: 34196652

  31. Choi, Y. H., Jung, H., Buys, S., Daly, M., John, E. M., Hopper, J., Andrulis, I., Terry, M. B., & Briollais, L. (2021). A competing risks model with binary time varying covariates for estimation of breast cancer risks in BRCA1 families. Statistical Methods in Medical Research30(9), 2165–2183. PMID: 34232831

  32. Knight, J. A., Kehm, R. D., Schwartz, L., Frost, C. J., Chung, W. K., Colonna, S., Keegan, T. H. M., Goldberg, M., Houghton, L. C., Hanna, D., Glendon, G., Daly, M. B., Buys, S. S., Andrulis, I. L., John, E. M., Bradbury, A. R., & Terry, M. B. (2021). Prepubertal Internalizing Symptoms and Timing of Puberty Onset in Girls. American Journal of Epidemiology190(3), 431–438. PMID: 33057572

  33. Espin-Garcia, O., Craiu, R. V., & Bull, S. B. (2021). Two-phase sample selection strategies for design and analysis in post-genome-wide association fine-mapping studies. Statistics in Medicine40(30), 6792–6817. PMID: 34596256

  34. Goodwin P. J. (2021). Extended Aromatase Inhibitors in Hormone-Receptor-Positive Breast Cancer. The New England Journal of Medicine385(5), 462–463. 1. PMID: 34320293.

  35. Lee, S. M., Mitchell, R., Knight, J. A., Mazzulli, T., Relton, C., Khodayari Moez, E., & Hung, R. J. (2021). Early-childhood cytomegalovirus infection and children's neurocognitive development. International Journal of Epidemiology50(2), 538–549. PMID: 33306803.

  36. Goodwin P.J., Dowling R.J.O., Ennis M., Chen B.E., Parulekar W.R., Shepherd L.E., Burnell M.J., Vandermeer R., Molckovsky A., Gurjal A., Gelmon K.A., Ligibel J.A., Hershman D., Mayer I.A., Whelan TJ, Hobday TJ, Rastogi P, Rabaglio-Poretti M, Lemieux J, Thompson AM, Rea DW, Stambolic V. (2021).  Effect of metformin on metabolic factors in MA.32 – A randomized trial in Early-Stage Breast Cancer. NPJ Breast Cancer 7, 74. [Full texts]

  37. Lohmann, A. E., Soldera, S. V., Pimentel, I., Ribnikar, D., Ennis, M., Amir, E., & Goodwin, P. J. (2021). Association of Obesity With Breast Cancer Outcome in Relation to Cancer Subtypes: A Meta-Analysis. Journal of the National Cancer Institute113(11), 1465–1475. PMID: 33620467

  38. MacInnis, R. J., Knight, J. A., Chung, W. K., Milne, R. L., Whittemore, A. S., Buchsbaum, R., Liao, Y., Zeinomar, N., Dite, G. S., Southey, M. C., Goldgar, D., Giles, G. G., Kurian, A. W., kConFab Investigators, Andrulis, I. L., John, E. M., Daly, M. B., Buys, S. S., Phillips, K. A., Hopper, J. L., … Terry, M. B. (2021). Comparing 5-Year and Lifetime Risks of Breast Cancer using the Prospective Family Study Cohort. Journal of the National Cancer Institute113(6), 785–791. PMID: 33301022

  39. Ong, S. W., Jassal, S. V., Porter, E. C., Min, K. K., Uddin, A., Cafazzo, J. A., Rac, V. E., Tomlinson, G., & Logan, A. G. (2021). Digital Applications Targeting Medication Safety in Ambulatory High-Risk CKD Patients: Randomized Controlled Clinical Trial. Clinical Journal of the American Society of Nephrology : CJASN16(4), 532–542. PMID: 33737321

  40. Pimentel I., Chen B.E, Lohmann A.E, Ennis M, Ligibel J., Shepherd L., Hershman D.L., Whelan T., Stambolic V., Mayer I., Hobday T., Lemieux J., Thompaon A., Rastogi P., Gelmon K., Rae D., Rabaglio M., Ellard S., Mates M., Bedard P., Pitre L., Vandenberg T., Dowling R.J.O., Parulekar W., Goodwin P.J. (2021). The effect of metformin on sex hormones Canadian Cancer Trials Group MA.32. J Natl Cancer Inst, 113 (2), 192-198. PMID: 33527137

  41. Retnakaran, R., Wen, S. W., Tan, H., Zhou, S., Ye, C., Shen, M., Smith, G. N., & Walker, M. C. (2021). Spousal Concordance of Cardiovascular Risk Factors in Newly Married Couples in China. JAMA Network Open4(12), e2140578. PMID: 34935919

  42. Retnakaran, R., Emery, A., Ye, C., Harris, S. B., Reichert, S. M., McInnes, N., Gerstein, H. C., Thorpe, K. E., Kramer, C. K., & Zinman, B. (2021). Short-term intensive insulin as induction and maintenance therapy for the preservation of beta-cell function in early type 2 diabetes (RESET-IT Main): A 2-year randomized controlled trial. Diabetes, Obesity & Metabolism23(8), 1926–1935. PMID: 33956387

  43. Xu, J., Xu, W., & Briollais, L. (2021). A Bayes factor approach with informative prior for rare genetic variant analysis from next generation sequencing data. Biometrics77(1), 316–328. [Full texts]

  44. Kachuri L, Johansson M, Rashkin SR, Graff RE, Bossé Y, Manem V, Caporaso NE, Landi MT, Christiani DC, Vineis P, Liu G, Scelo G, Zaridze D, Shete SS, Albanes D, Aldrich MC, Tardón A, Rennert G, Chen C, Goodman GE, Doherty JA, Bickeböller H, Field JK, Davies MP, Dawn Teare M, Kiemeney LA, Bojesen SE, Haugen A, Zienolddiny S, Lam S, Le Marchand L, Cheng I, Schabath MB, Duell EJ, Andrew AS, Manjer J, Lazarus P, Arnold S, McKay JD, Emami NC, Warkentin MT, Brhane Y, Obeidat M, Martin RM, Relton C, Davey Smith G, Haycock PC, Amos CI, Brennan P, Witte JS*, Hung RJ*. (2020). Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility. Nature Communications 11(1):27. PMID: 31911640

  45. Zhang, A. W., & Campbell, K. R. (2020). Computational modelling in single-cell cancer genomics: methods and future directions. Physical Biology17(6), 061001. 1. PMID: 32759485.

  46. Romanescu, R. G., Green, J., Andrulis, I. L., & Bull, S. B. (2020). Gene-based and pathway-based testing for rare-variant association in affected sib pairs. Genetic Epidemiology44(4), 368–381 PMID: 32237178

  47. Casas-Guzik, L., Ye, C., & Retnakaran, R. (2020). Association of Time With Reliability of Maternal Recall of Infant Birth Weight. JAMA Pediatrics174(12), 1208–1210. PMID: 32364580

  48. Goodwin, P. J., Segal, R. J., Vallis, M., Ligibel, J. A., Pond, G. R., Robidoux, A., Findlay, B., Gralow, J. R., Mukherjee, S. D., Levine, M., & Pritchard, K. I. (2020). The LISA randomized trial of a weight loss intervention in postmenopausal breast cancer. NPJ Breast Cancer6, 6. PMID: 32133391

  49. Lakhal-Chaieb, L., Simard, J., & Bull, S. (2020). Sequence kernel association test for survival outcomes in the presence of a non-susceptible fraction. Biostatistics (Oxford, England)21(3), 518–530. 1. PMID: 30590388.

  50. Michalsky, C.A., Hung, R.J., Seeto R. A, Dennis, C-L, Brooks JD, Henderson J, Levitan R, Lye SJ, Matthews S, Knight, J.A. (2020).Maternal cannabis use and adverse birth outcomes. BMC Pregnancy Childbirth 20(1):771. PMID: 33308186

  51. Wu, Y., Lye, S., Dennis, C. L., & Briollais, L. (2020). Exclusive breastfeeding can attenuate body-mass-index increase among genetically susceptible children: A longitudinal study from the ALSPAC cohort. PLoS Genetics16(6), e1008790. PMID: 32525877

  52. Retnakaran, R., & Shah, B. R. (2020). Divergent Trajectories of Cardiovascular Risk Factors in the Years Before Pregnancy in Women With and Without Gestational Diabetes Mellitus: A Population-Based Study. Diabetes Care43(10), 2500–2508. PMID: 32796027

  53. Zhang, A. W., O'Flanagan, C., Chavez, E. A., Lim, J. L. P., Ceglia, N., McPherson, A., Wiens, M., Walters, P., Chan, T., Hewitson, B., Lai, D., Mottok, A., Sarkozy, C., Chong, L., Aoki, T., Wang, X., Weng, A. P., McAlpine, J. N., Aparicio, S., Steidl, C., Campbell, K.R., Shah, S. P. (2019). Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling. Nature Methods16(10), 1007–1015. PMID: 31501550

  54. Campbell, K. R., Steif, A., Laks, E., Zahn, H., Lai, D., McPherson, A., Farahani, H., Kabeer, F., O'Flanagan, C., Biele, J., Brimhall, J., Wang, B., Walters, P., IMAXT Consortium, Bouchard-Côté, A., Aparicio, S., & Shah, S. P. (2019). clonealign: statistical integration of independent single-cell RNA and DNA sequencing data from human cancers. Genome Biology20(1), 54. PMID: 30866997

  55. Warkentin, M. T., Lam, S., & Hung, R. J. (2019). Determinants of impaired lung function and lung cancer prediction among never-smokers in the UK Biobank cohort. EBioMedicine47, 58–64. PMID: 31495719

  56. Choi, Y. H., Lakhal-Chaieb, L., Kröl, A., Yu, B., Buchanan, D., Ahnen, D., Le Marchand, L., Newcomb, P. A., Win, A. K., Jenkins, M., Lindor, N. M., & Briollais, L. (2019). Risks of Colorectal Cancer and Cancer-Related Mortality in Familial Colorectal Cancer Type X and Lynch Syndrome Families. Journal of the National Cancer Institute111(7), 675–683. 8. PMID: 30380125

  57. Dowling, R.J.O., Kalinsky, K., Hayes, D.F., Bidard, F-C., Cescon, D.W., Chandarlapaty, S., Deasy, J.O., Dowsett, M., Gray, R.J., Henry, N.L., Meric-Bernstam, F., Perlmutter, J., Sledge, G.W., Bratman, S.V., Carey, L.A., Chang, M.C., DeMichele, A., Ennis, M., Jerzak, K.J., Korde, L.A., Lohmann, A.E., Mamounas E.P., Parulekar, W.R., Regan, M.M., Schramek, D., Stambolic, V., Thorat, M.A., Whelan, T.J., Wolff, AC., Woodgett, J.R., Sparano, J.A., Goodwin, P.J. (2019). Toronto workshop on late recurrence in estrogen receptor positive breast cancer Part 1: Late recurrence – current understanding, clinical considerations. Journal of the National Cancer Institute Cancer Spectrum 3(4), pkz050.  PMID: 32337479

  58. Houghton, L. C., Knight, J. A., Wei, Y., Romeo, R. D., Goldberg, M., Andrulis, I. L., Bradbury, A. R., Buys, S. S., Daly, M. B., John, E. M., Chung, W. K., Santella, R. M., Stanczyk, F. Z., & Terry, M. B. (2019). Association of Prepubertal and Adolescent Androgen Concentrations With Timing of Breast Development and Family History of Breast Cancer. JAMA Network Open2(2), e190083. PMID: 30794303 PMID: 30794303

  59. Kim, S. A., Brossard, M., Roshandel, D., Paterson, A. D., Bull, S. B., & Yoo, Y. J. (2019). gpart: human genome partitioning and visualization of high-density SNP data by identifying haplotype blocks. Bioinformatics (Oxford, England)35(21), 4419–4421.  PMID: 31070701

  60. Retnakaran, R., & Shah, B. R. (2019). Glucose screening in pregnancy and future risk of cardiovascular disease in women: a retrospective, population-based cohort study. The Lancet. Diabetes & Endocrinology7(5), 378–384. PMID: 30928459

  61. Stock, D., Knight, J. A., Raboud, J., Cotterchio, M., Strohmaier, S., Willett, W., Eliassen, A. H., Rosner, B., Hankinson, S. E., & Schernhammer, E. (2019). Rotating night shift work and menopausal age. Human Reproduction (Oxford, England)34(3), 539–548. PMID: 30753548

  62. Retnakaran, R., Ye, C., Hanley, A. J., Connelly, P. W., Sermer, M., & Zinman, B. (2019). Screening Glucose Challenge Test in Pregnancy Can Identify Women With an Adverse Postpartum Cardiovascular Risk Factor Profile: Implications for Cardiovascular Risk Reduction. Journal of the American Heart Association8(21), e014231. PMID: 31657272

  63. Shen SY, Singhanai R, Fehringer G, Chakravarthy A, Roehrl MHA, Chadwick D, Zuzarte PC, Borgida A, Wang TT, Li T, Kis O, Zhao Z, Spreafico A, da Silva Medina T, Wang Y, Roulois D, Ettayebi I, Chen Z, Chow S, Murphy T, Arrudal A, O'Kane GM, Liu J, Mansour M, McPherson JD, O'Brien C, Leigh N, Bedard PL, Fleshner N, Liu G, Minden MD, Gallinger S, Goldenberg A, Pugh TJ, Hoffman MM, Bratman SV, Hung RJ*, DeCarvalho DD*.(2018). Highly sensitive tumor detection and classification using methylome analysis of plasma cell-free DNA.  Nature, 563(7732):579-583. PMID: 30429608

  64. Anderson, L. N., Knight, J. A., Hung, R. J., Hewko, S. L., Seeto, R. A., Martin, M. J., Fleming, A., Maguire, J. L., Matthews, S. G., Murphy, K. E., Okun, N., Jenkins, J. M., Lye, S. J., Bocking, A., & Ontario Birth Study Collaboration (2018). The Ontario Birth Study: A prospective pregnancy cohort study integrating perinatal research into clinical care. Paediatric and Perinatal Epidemiology32(3), 290–301. PMID: 29750375

  65. Bull, S.B., Andrulis, I.L., Paterson. A.D. (2018). Statistical Challenges in High-Dimensional Molecular and Genetic Epidemiology. Canadian Journal of Statistics, 46(1): 24-49. [Full text]

  66. Kachuri L, Saarela O, Bojesen SE, Davey Smith G, Liu G, Landi MT, Caporaso NE, Christiani DC, Johansson M, Panico S, Overvad K, Trichopoulou A, Vineis P, Scelo G, Zaridze D, Wu X, Albanes D, Diergaarde B, Lagiou P, Macfarlane GJ, Aldrich MC, Tardón A, Rennert G, Olshan AF, Weissler MC, Chen C, Goodman GE, Doherty JA, Ness AR, Bickeböller H, Wichmann HE, Risch A, Field JK, Teare MD, Kiemeney LA, van der Heijden EHFM, Carroll JC, Haugen A, Zienolddiny S, Skaug V, Wünsch-Filho V, Tajara EH, Ayoub Moysés R, Daumas Nunes F, Lam S, Eluf-Neto J, Lacko M, Peters WHM, Le Marchand L, Duell EJ, Andrew AS, Franceschi S, Schabath MB, Manjer J, Arnold S, Lazarus P, Mukeriya A, Swiatkowska B, Janout V, Holcatova I, Stojsic J, Mates D, Lissowska J, Boccia S, Lesseur C, Zong X, McKay JD, Brennan P, Amos CI, Hung RJ. (2018). Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers.  Int. J. Epidemiology, 48(3), 751-766. PMID: 30059977

  67. Knight, J. A., Blackmore, K. M., Fan, J., Malone, K. E., John, E. M., Lynch, C. F., Vachon, C. M., Bernstein, L., Brooks, J. D., Reiner, A. S., Liang, X., Woods, M., WECARE Study Collaborative Group, & Bernstein, J. L. (2018). The association of mammographic density with risk of contralateral breast cancer and change in density with treatment in the WECARE study. Breast Cancer Research : BCR20(1), 23. PMID: 29566728

  68. Logan, A. G., & Jassal, S. V. (2018). Building a Stronger Care Loop Through mHealth Technology. JAMA Internal Medicine178(6), 809–811. PMID: 29710104.

  69. Retnakaran, R., Wen, S. W., Tan, H., Zhou, S., Ye, C., Shen, M., Smith, G. N., & Walker, M. C. (2018). Association of Timing of Weight Gain in Pregnancy With Infant Birth Weight. JAMA Pediatrics172(2), 136–142. PMID: 29279903

  70. McKay JD*, Hung RJ*, Han Y, Zong X, Carreras-Torres R, Christiani DC, Caporaso NE, Johansson M, Xiao X, Li Y, Byun J, Dunning A, Pooley KA, Qian DC, Ji X, Liu G, Timofeeva MN, Bojesen SE, Wu X, Le Marchand L, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Shen H, Hong YC, Yuan JM, Bertazzi PA, Pesatori AC, Ye Y, Diao N, Su L, Zhang R, Brhane Y, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman CA, Wilkens LR, Fernandez-Somoano A, Fernandez-Tardon G, van der Heijden HFM, Kim JH, Dai J, Hu Z, Davies MPA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Doherty JA, Barnett MP, Chen C, Goodman GE, Cox A, Taylor F, Woll P, Brüske I, Wichmann HE, Manz J, Muley TR, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd FA, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Koh WP, Gao YT, Houlston RS, McLaughlin J, Stevens VL, Joubert P, Lamontagne M, Nickle DC, Obeidat M, Timens W, Zhu B, Song L, Kachuri L, Artigas MS, Tobin MD, Wain LV; SpiroMeta Consortium, Rafnar T, Thorgeirsson TE, Reginsson GW, Stefansson K, Hancock DB, Bierut LJ, Spitz MR, Gaddis NC, Lutz SM, Gu F, Johnson EO, Kamal A, Pikielny C, Zhu D, Lindströem S, Jiang X, Tyndale RF, Chenevix-Trench G, Beesley J, Bossé Y, Chanock S, Brennan P, Landi MT, Amos CI. (2017). Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Nature Genetics. 49(7):1126-1132. PMID: 28604730

  71. Briollais, L., Ozcelik, H., Xu, J., Kwiatkowski, M., Lalonde, E., Sendorek, D. H., Fleshner, N. E., Recker, F., Kuk, C., Olkhov-Mitsel, E., Savas, S., Hanna, S., Juvet, T., Hunter, G. A., Friedlander, M., Li, H., Chadwick, K., Prassas, I., Soosaipillai, A., Randazzo, M., … Zlotta, A. R. (2017). Germline Mutations in the Kallikrein 6 Region and Predisposition for Aggressive Prostate Cancer. Journal of the National Cancer Institute109(4), 10.1093/jnci/djw258. 1.    PMID: 28376164

  72. Knight, J. A., Fan, J., Malone, K. E., John, E. M., Lynch, C. F., Langballe, R., Bernstein, L., Shore, R. E., Brooks, J. D., Reiner, A. S., Woods, M., Liang, X., Bernstein, J. L., & WECARE Study Collaborative Group (2017). Alcohol consumption and cigarette smoking in combination: A predictor of contralateral breast cancer risk in the WECARE study. International Journal of Cancer141(5), 916–924. PMID: 28524234

  73. Wu, Y. Y., Lye, S., & Briollais, L. (2017). The role of early life growth development, the FTO gene and exclusive breastfeeding on child BMI trajectories. International Journal of Epidemiology46(5), 1512–1522. PMID: 29040503

  74. Yoo, Y. J., Sun, L., Poirier, J. G., Paterson, A. D., & Bull, S. B. (2017). Multiple linear combination (MLC) regression tests for common variants adapted to linkage disequilibrium structure. Genetic Epidemiology41(2), 108–121. PMID: 27885705

  75. Zong, X., Pole, J. D., Grundy, P. E., Mahmud, S. M., Parker, L., & Hung, R. J. (2017). Second malignant neoplasms after childhood non-central nervous system embryonal tumours in North America: A population-based study. European Journal of Cancer (Oxford, England)84, 173–183.  PMID: 28822326